He is on the books of Deportivo Cali Women and wears shirt number 21. At international level, he features for Colombia U17 Women. His main role on the pitch is Midfield.

Over 1 appearances in the Colombian Liga Betplay Femenina 2026, Isabella Santa Espinosa contributed 0 goals and 0 assists, completed 0 key passes from 0 total passes, and posted a passing accuracy of -.